TY - GEN
T1 - Detection of the propagating direction of electrical wavefront in atrial fibrillation
AU - Du, Dongping
AU - Du, Yuncheng
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2016/10/13
Y1 - 2016/10/13
N2 - Atrial Fibrillation (AF) is one of the most common sustained arrhythmia, which can increase the risk of heart failure and stroke. Understanding the complex electrical dynamics of AF and correctly targeting AF sources for ablation therapies remain challenging in clinical practice. This is due to the incapability to reconstruct the electrical dynamic of AF, and lack of efficient approach for AF source identification. This paper builds a multi-sale framework for modeling of the abnormal electrical propagation in AF initiated by triggers from Pulmonary Veins (PVs). A new algorithm is developed to detect the propagating direction of electrical wavefronts. The detection algorithm is further validated using modeling results. The developed multi-scale framework and the detection algorithm will contribute to AF diagnosis and potentially improve the treatment outcomes of AF ablations.
AB - Atrial Fibrillation (AF) is one of the most common sustained arrhythmia, which can increase the risk of heart failure and stroke. Understanding the complex electrical dynamics of AF and correctly targeting AF sources for ablation therapies remain challenging in clinical practice. This is due to the incapability to reconstruct the electrical dynamic of AF, and lack of efficient approach for AF source identification. This paper builds a multi-sale framework for modeling of the abnormal electrical propagation in AF initiated by triggers from Pulmonary Veins (PVs). A new algorithm is developed to detect the propagating direction of electrical wavefronts. The detection algorithm is further validated using modeling results. The developed multi-scale framework and the detection algorithm will contribute to AF diagnosis and potentially improve the treatment outcomes of AF ablations.
KW - Atrial Fibrillation
KW - Direction of wavefront propagation
KW - Multi-scale modeling
KW - Pulmonary vein
UR - http://www.scopus.com/inward/record.url?scp=85009067870&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2016.7591299
DO - 10.1109/EMBC.2016.7591299
M3 - Conference contribution
C2 - 28268888
AN - SCOPUS:85009067870
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 2749
EP - 2752
BT - 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Y2 - 16 August 2016 through 20 August 2016
ER -