TY - JOUR
T1 - Detachment Force of the Helical Anchor in Mitral Annulus
AU - Zeng, Ganhe
AU - Li, Gang
AU - Jia, Yunchao
AU - Chen, Si
AU - Chen, Pengyang
AU - He, Zhaoming
N1 - Funding Information:
The authors acknowledge financial support from the National Natural Science Foundation of China (No. 51805218 ).
Publisher Copyright:
© 2021 The Author(s)
PY - 2021/12
Y1 - 2021/12
N2 - Helical anchors are used in transcatheter mitral valve repair. The aim of the current study was to investigate effect of helical anchor design, anchored position and biting depth on the detachment force in an in-vitro experiment. Mitral annulus was excised from 36 fresh porcine hearts and mounted in an unaxial test rig. Seven helical anchors were made of stainless steel based on the geometric parameters: outer diameter, wire diameter, and pitch. The helical anchors were screwed in at 3 to 9 o'clock positions of the posterior annulus, namely, P3-9, and pulled out. The pullout force was measured with the maximal pullout force defined as the detachment force. The detachment force within the medial, lateral and central positions were comparable (p > =0.069). The detachment force at P6 was lowest compared with the medial and lateral positions, and was 5.459 ± 0.193 N, 5.586 ± 0.113 N, 8.911 ± 0.250 N for the anchors in the outer diameters of 3, 4, 5 mm, respectively at the pitch of 2 mm and the wire diameter of 0.4 mm and biting depth of 3 coils. The detachment force increased with the outer and wire diameters, but was not affected by the pitch at the biting depth of 3 coils (p ≥ 0.279). The detachment force of the helical anchor is lowest in the central posterior annulus region, and the biting depth in 3 or more coils is recommended. The helical anchor is stronger than the suture.
AB - Helical anchors are used in transcatheter mitral valve repair. The aim of the current study was to investigate effect of helical anchor design, anchored position and biting depth on the detachment force in an in-vitro experiment. Mitral annulus was excised from 36 fresh porcine hearts and mounted in an unaxial test rig. Seven helical anchors were made of stainless steel based on the geometric parameters: outer diameter, wire diameter, and pitch. The helical anchors were screwed in at 3 to 9 o'clock positions of the posterior annulus, namely, P3-9, and pulled out. The pullout force was measured with the maximal pullout force defined as the detachment force. The detachment force within the medial, lateral and central positions were comparable (p > =0.069). The detachment force at P6 was lowest compared with the medial and lateral positions, and was 5.459 ± 0.193 N, 5.586 ± 0.113 N, 8.911 ± 0.250 N for the anchors in the outer diameters of 3, 4, 5 mm, respectively at the pitch of 2 mm and the wire diameter of 0.4 mm and biting depth of 3 coils. The detachment force increased with the outer and wire diameters, but was not affected by the pitch at the biting depth of 3 coils (p ≥ 0.279). The detachment force of the helical anchor is lowest in the central posterior annulus region, and the biting depth in 3 or more coils is recommended. The helical anchor is stronger than the suture.
KW - Detachment force
KW - Helical anchor design
KW - Mitral valve repair
KW - Tissue mechanics
UR - http://www.scopus.com/inward/record.url?scp=85118345947&partnerID=8YFLogxK
U2 - 10.1016/j.medntd.2021.100098
DO - 10.1016/j.medntd.2021.100098
M3 - Article
AN - SCOPUS:85118345947
SN - 2590-0935
VL - 12
JO - Medicine in Novel Technology and Devices
JF - Medicine in Novel Technology and Devices
M1 - 100098
ER -