TY - JOUR
T1 - Design Considerations for Artificial Water Channel-Based Membranes
AU - Song, Woochul
AU - Lang, Chao
AU - Shen, Yue Xiao
AU - Kumar, Manish
N1 - Funding Information:
The authors acknowledge financial support from a National Science Foundation CAREER grant (CBET-1552571) to MK for this work. Support was also provided through CBET-1705278 and DMR-1709522 for various aspects of this work.
Publisher Copyright:
© Copyright 2018 by Annual Reviews. All rights reserved.
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Aquaporins (AQPs) are naturally occurring water channel proteins. They can facilitate water molecule translocation across cellular membranes with exceptional selectivity and high permeability that are unmatched in synthetic membrane systems. These unique properties of AQPs have led to their use as functional elements in membranes in recent years. However, the intricate nature of AQPs and concerns regarding their stability and processability have encouraged researchers to develop synthetic channels that mimic the structure and properties of AQPs and other biological water-conducting channels. These channels have been termed artificial water channels. This article reviews current progress and provides a historical perspective as well as an outlook toward developing scalable membranes based on artificial water channels.
AB - Aquaporins (AQPs) are naturally occurring water channel proteins. They can facilitate water molecule translocation across cellular membranes with exceptional selectivity and high permeability that are unmatched in synthetic membrane systems. These unique properties of AQPs have led to their use as functional elements in membranes in recent years. However, the intricate nature of AQPs and concerns regarding their stability and processability have encouraged researchers to develop synthetic channels that mimic the structure and properties of AQPs and other biological water-conducting channels. These channels have been termed artificial water channels. This article reviews current progress and provides a historical perspective as well as an outlook toward developing scalable membranes based on artificial water channels.
KW - aquaporins
KW - artificial water channels
KW - biomimetic membranes
KW - membrane fabrication
KW - membrane-based separations
UR - http://www.scopus.com/inward/record.url?scp=85048362591&partnerID=8YFLogxK
U2 - 10.1146/annurev-matsci-070317-124544
DO - 10.1146/annurev-matsci-070317-124544
M3 - Review article
AN - SCOPUS:85048362591
SN - 1531-7331
VL - 48
SP - 57
EP - 82
JO - Annual Review of Materials Research
JF - Annual Review of Materials Research
ER -