Design Considerations for Artificial Water Channel-Based Membranes

Woochul Song, Chao Lang, Yue Xiao Shen, Manish Kumar

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

Aquaporins (AQPs) are naturally occurring water channel proteins. They can facilitate water molecule translocation across cellular membranes with exceptional selectivity and high permeability that are unmatched in synthetic membrane systems. These unique properties of AQPs have led to their use as functional elements in membranes in recent years. However, the intricate nature of AQPs and concerns regarding their stability and processability have encouraged researchers to develop synthetic channels that mimic the structure and properties of AQPs and other biological water-conducting channels. These channels have been termed artificial water channels. This article reviews current progress and provides a historical perspective as well as an outlook toward developing scalable membranes based on artificial water channels.

Original languageEnglish
Pages (from-to)57-82
Number of pages26
JournalAnnual Review of Materials Research
Volume48
DOIs
StatePublished - Jul 1 2018

Keywords

  • aquaporins
  • artificial water channels
  • biomimetic membranes
  • membrane fabrication
  • membrane-based separations

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