Deep homology? Uncanny similarities of humans and flies uncovered by evo-devo

Research output: Book/ReportBookpeer-review

10 Scopus citations


Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

Original languageEnglish
PublisherCambridge University Press
Number of pages272
ISBN (Electronic)9781316550175
ISBN (Print)9781107147188
StatePublished - Jan 1 2017


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