Abstract
Readily available triethylammonium 1-(2-oxoindolin-3-ylidene)-2- aroylethanethiolates are efficiently converted into a variety of fully substituted thiophene derivatives by copper(I)-catalyzed denitrogenative reactions with terminal alkynes and N-sulfonyl azides. This new reaction simultaneously installs C-N, C-S, and C-C bonds, allowing direct formation of highly functionalized thiophenes with a wide diversity in substituents in a one-pot manner. A plausible mechanism for the domino process is proposed.
Original language | English |
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Pages (from-to) | 3656-3659 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 16 |
Issue number | 14 |
DOIs | |
State | Published - Jul 18 2014 |