Copper and cobalt co-catalyzed aerobic oxidative cross-dehydrogenative coupling reaction of (benzo)azoles

Yanrong Li, Fen Qian, Xia Ge, Tao Liu, Hitesh B. Jalani, Hongjian Lu, Guigen Li

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The dehydrogenative cross-coupling (CDC) reaction of diversely substituted azoles, synergistically catalyzed by copper and cobalt, is reported. This protocol represents the first example of the use of air as an oxidant to carry out this chemical reaction. The process provides a convenient and economical method for the construction of valuable unsymmetrical bis-heteroaryl compounds, including bis-benzoazole compounds that were not obtained in previous catalytic CDC reactions.

Original languageEnglish
Pages (from-to)5797-5802
Number of pages6
JournalGreen Chemistry
Volume21
Issue number21
DOIs
StatePublished - 2019

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