Ahstract-A crucial and time-sensitive task when any disaster occurs is to rescue victims and distribute resources to the right groups and locations. This task is challenging in populated urban areas, due to a huge burst of help requests made in a very short period. To improve the efficiency of the emergency response in the immediate aftermath of a disaster, we propose a heuristic multi-Agent reinforcement learning scheduling algorithm, named as ResQ, which can effectively schedule a rapid deployment of volunteers to rescue victims in dynamic settings. The core concept is to quickly identify victims and volunteers from social network data and then schedule rescue parties with an adaptive learning algorithm. This framework performs two key functions: 1) identify trapped victims and volunteers, and 2) optimize the volunteers' rescue strategy in a complex time-sensitive environment. The proposed ResQ algorithm can speed up the training processes through a heuristic function which reduces the state-Action space by identifying a set of particular actions over others. Experimental results showed that the proposed heuristic multi-Agent reinforcement learning based scheduling outperforms several state-of-Art methods, in terms of both reward rate and response times.