Conversion of aldimines to secondary amines using iron-catalysed hydrosilylation

Anu Saini, Cecilia R. Smith, Francis S. Wekesa, Amanda K. Helms, Michael Findlater

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Iron-catalyzed hydrosilylation of imines to amines using a well-defined iron complex is reported. This method employs relatively mild conditions, by reaction of imine, (EtO) 3 SiH in a 1 : 2 ratio in the presence of 1 mol% precatalyst ([BIAN]Fe(η 6 -toluene), 3, BIAN = bis(2,6-diisopropylaniline)acenaphthene) at 70 °C. A broad scope of imines was readily converted into the corresponding secondary amines without the need for precatalyst activators.

Original languageEnglish
Pages (from-to)9368-9372
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume16
Issue number48
DOIs
StatePublished - 2018

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