Complete mitochondrial genome sequences of three bats species and whole genome mitochondrial analyses reveal patterns of codon bias and lend support to a basal split in Chiroptera

P. R. Meganathan, Heidi J.T. Pagan, Eve S. McCulloch, Richard D. Stevens, David A. Ray

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Order Chiroptera is a unique group of mammals whose members have attained self-powered flight as their main mode of locomotion. Much speculation persists regarding bat evolution; however, lack of sufficient molecular data hampers evolutionary and conservation studies. Of ~. 1200 species, complete mitochondrial genome sequences are available for only eleven. Additional sequences should be generated if we are to resolve many questions concerning these fascinating mammals. Herein, we describe the complete mitochondrial genomes of three bats: Corynorhinus rafinesquii, Lasiurus borealis and Artibeus lituratus. We also compare the currently available mitochondrial genomes and analyze codon usage in Chiroptera. C. rafinesquii, L. borealis and A. lituratus mitochondrial genomes are 16438. bp, 17048. bp and 16709. bp, respectively. Genome organization and gene arrangements are similar to other bats. Phylogenetic analyses using complete mitochondrial genome sequences support previously established phylogenetic relationships and suggest utility in future studies focusing on the evolutionary aspects of these species. Comprehensive analyses of available bat mitochondrial genomes reveal distinct nucleotide patterns and synonymous codon preferences corresponding to different chiropteran families. These patterns suggest that mutational and selection forces are acting to different extents within Chiroptera and shape their mitochondrial genomes.

Original languageEnglish
Pages (from-to)121-129
Number of pages9
JournalGene
Volume492
Issue number1
DOIs
StatePublished - Jan 15 2012

Keywords

  • Artibeus lituratus
  • Codon usage bias
  • Corynorhinus rafinesquii
  • Evolutionary forces
  • Lasiurus borealis
  • Mitochondrial genome

Fingerprint

Dive into the research topics of 'Complete mitochondrial genome sequences of three bats species and whole genome mitochondrial analyses reveal patterns of codon bias and lend support to a basal split in Chiroptera'. Together they form a unique fingerprint.

Cite this