Cobalt-Catalyzed Decarboxylative C-H (Hetero)Arylation for the Synthesis of Arylheteroarenes and Unsymmetrical Biheteroaryls

Yanrong Li, Fen Qian, Mengshi Wang, Hongjian Lu, Guigen Li

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

A cobalt-catalyzed decarboxylative cross-coupling reaction of (hetero)aryl carboxylic acids with benzothiazoles or benzoxazoles is reported. This represents a first example of metal-catalyzed decarboxylative C-H heteroarylation of benzo-fused heterocycles. The transformation provides a convenient route, with good yields and functional group tolerance, to various important arylheteroaryl and unsymmetrical biheteroaryl structural motifs.

Original languageEnglish
Pages (from-to)5589-5592
Number of pages4
JournalOrganic Letters
Volume19
Issue number20
DOIs
StatePublished - Oct 20 2017

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