Abstract
The reliability of supramolecular synthons in co-crystals involving naproxen and mefenamic acid is investigated. The carboxylic acid⋯pyridine synthon is exceptionally reliable; however, we observe synthon breakdown and a rare pyridyl dimer in a co-crystal with mefenamic acid. A Cambridge Structural Database survey supports the rarity of this motif in acid-bipyridine co-crystals.
| Original language | English |
|---|---|
| Pages (from-to) | 6377-6381 |
| Number of pages | 5 |
| Journal | CrystEngComm |
| Volume | 20 |
| Issue number | 41 |
| DOIs | |
| State | Published - 2018 |
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Zheng, Q., Rood, S. L., Unruh, D. K., & Hutchins, K. M. (2018). Co-crystallization of anti-inflammatory pharmaceutical contaminants and rare carboxylic acid-pyridine supramolecular synthon breakdown. CrystEngComm, 20(41), 6377-6381. https://doi.org/10.1039/c8ce01492b