TY - JOUR
T1 - Clinical Implications of Current Findings in Neurodevelopment
AU - Knapp, Penelope
AU - Mastergeorge, Ann M.
PY - 2009/3
Y1 - 2009/3
N2 - Research in the last decade has advanced our knowledge about biological factors underlying neurodevelopmental processes in childhood. Genetic research has gone beyond mapping the human genome to identifying epigenetic factors and explicating gene-environment interactions. Biological markers of vulnerability to specific disorders have been identified. The functions of and interactions between neuroanatomic regions have been illuminated by new imaging and other noninvasive techniques, such as EEG, event-related potentials, and functional magnetic resonance imaging, that allow us to link earliest signs of disorders to neurological changes. This article provides an overview of current findings in neurodevelopment, and discusses diagnostic factors, prevention and intervention, and clinical implications.
AB - Research in the last decade has advanced our knowledge about biological factors underlying neurodevelopmental processes in childhood. Genetic research has gone beyond mapping the human genome to identifying epigenetic factors and explicating gene-environment interactions. Biological markers of vulnerability to specific disorders have been identified. The functions of and interactions between neuroanatomic regions have been illuminated by new imaging and other noninvasive techniques, such as EEG, event-related potentials, and functional magnetic resonance imaging, that allow us to link earliest signs of disorders to neurological changes. This article provides an overview of current findings in neurodevelopment, and discusses diagnostic factors, prevention and intervention, and clinical implications.
KW - Biological factors
KW - Developmental trajectories
KW - Early indicators
KW - Neurodevelopment
KW - Neuroplasticity
UR - http://www.scopus.com/inward/record.url?scp=60549111249&partnerID=8YFLogxK
U2 - 10.1016/j.psc.2008.11.006
DO - 10.1016/j.psc.2008.11.006
M3 - Review article
C2 - 19248924
AN - SCOPUS:60549111249
SN - 0193-953X
VL - 32
SP - 177
EP - 197
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
IS - 1
ER -