Chronic L-citrulline supplementation improves cardiac sympathovagal balance in obese postmenopausal women: A preliminary report

Alexei Wong, Oksana Chernykh, Arturo Figueroa

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The present study evaluated the impact of chronic L-citrulline (L-cit) supplementation on resting heart rate variability (HRV) and blood pressure (BP) in obese postmenopausal women. Participants were randomly assign to either an L-cit group (n = 12) or a control group (n = 11). HRV and BP were measured before and after 8 weeks. There were significant decreases (P < 0.05) in nLF (sympathetic activity), LnLF/LnHF (sympathovagal balance), and BP as well as a significant increase (P < 0.05) in nHF (vagal tone) following L-cit compared with no changes after control. Our findings indicate that L-cit supplementation improves sympathovagal balance in obese postmenopausal women.

Original languageEnglish
Pages (from-to)50-53
Number of pages4
JournalAutonomic Neuroscience: Basic and Clinical
Volume198
DOIs
StatePublished - Jul 1 2016

Keywords

  • Heart rate variability
  • L-citrulline
  • Sympathovagal balance

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