@article{290bb7c14f8044c7b3324c31f8b49b0c,
title = "Chiral N-phosphoryl imines: Design, synthesis and direct asymmetric addition reactions with diketones and diesters",
abstract = "Chiral N-phosphoryl imines derived from (S)-BINOL have been designed and synthesized in good to excellent chemical yields. These N-phosphoryl imines were found to react with diketones smoothly without the use of any bases. They can also serve as electrophiles for the reaction with diethyl malonate in the presence of potassium carbonate. Good yields (62% - quant) and excellent diastereoselectivities (up to 99:1 dr) have been achieved for 10 examples.",
author = "Hao Sun and Trideep Rajale and Yi Pan and Guigen Li",
note = "Funding Information: We gratefully acknowledge the financial support from the Robert A. Welch Foundation ( D-1361 to G.L.), NIH ( R03DA026960 ), NSFC (No. 20772056 , to Y.P.). This work was also partially supported by the Qing-Lan Program of Jiangsu Province (to Y.P.) and the Kua-Shi-Ji Program of the Education Ministry of China (to Y.P.). We thank them for their generous support. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Drug Abuse or the National Institutes of Health. ",
year = "2010",
month = aug,
day = "18",
doi = "10.1016/j.tetlet.2010.06.072",
language = "English",
volume = "51",
pages = "4403--4407",
journal = "Tetrahedron Letters",
issn = "0040-4039",
number = "33",
}