TY - JOUR
T1 - Childhood self-control forecasts the pace of midlife aging and preparedness for old age
AU - Richmond-Rakerd, Leah S.
AU - Caspi, Avshalom
AU - Ambler, Antony
AU - d’Arbeloff, Tracy
AU - de Bruine, Marieke
AU - Elliott, Maxwell
AU - Harrington, Hona Lee
AU - Hogan, Sean
AU - Houts, Renate M.
AU - Ireland, David
AU - Keenan, Ross
AU - Knodt, Annchen R.
AU - Melzer, Tracy R.
AU - Park, Sena
AU - Poulton, Richie
AU - Ramrakha, Sandhya
AU - Rasmussen, Line Jee Hartmann
AU - Sack, Elizabeth
AU - Schmidt, Adam T.
AU - Sison, Maria L.
AU - Wertz, Jasmin
AU - Hariri, Ahmad R.
AU - Moffitt, Terrie E.
N1 - Funding Information:
ACKNOWLEDGMENTS. Research was supported by grants from the National Institute on Aging (AG032282, AG049789), the UK Medical Research Council (P005918), and the Jacobs Foundation. The Dunedin Multidisciplinary Health and Development Study is supported by the New Zealand Health Research Council and the New Zealand Ministry of Business, Innovation and Employment. L.S.R.-R. was supported by a postdoctoral fellowship from the National Institute of Child Health and Human Development (T32-HD007376). M.E. was supported by the NSF Graduate Research Fellowship (DGE-1644868). L.J.H.R. was supported by a postdoctoral fellowship from the Lundbeck Foundation (R288-2018-380). J.W. was supported by a postdoctoral fellowship from the AXA Research Fund. We thank the Dunedin Study members, Unit research staff, Pacific Radiology Group staff, and Study founder Phil Silva.
Publisher Copyright:
© 2021 National Academy of Sciences. All rights reserved.
PY - 2021/1/19
Y1 - 2021/1/19
N2 - The ability to control one’s own emotions, thoughts, and behaviors in early life predicts a range of positive outcomes in later life, including longevity. Does it also predict how well people age? We studied the association between self-control and midlife aging in a population-representative cohort of children followed from birth to age 45 y, the Dunedin Study. We measured children’s self-control across their first decade of life using a multi-occasion/multiinformant strategy. We measured their pace of aging and aging preparedness in midlife using measures derived from biological and physiological assessments, structural brain-imaging scans, observer ratings, self-reports, informant reports, and administrative records. As adults, children with better self-control aged more slowly in their bodies and showed fewer signs of aging in their brains. By midlife, these children were also better equipped to manage a range of later-life health, financial, and social demands. Associations with children’s self-control could be separated from their social class origins and intelligence, indicating that self-control might be an active ingredient in healthy aging. Children also shifted naturally in their level of self-control across adult life, suggesting the possibility that self-control may be a malleable target for intervention. Furthermore, individuals’ self-control in adulthood was associated with their aging outcomes after accounting for their self-control in childhood, indicating that midlife might offer another window of opportunity to promote healthy aging.
AB - The ability to control one’s own emotions, thoughts, and behaviors in early life predicts a range of positive outcomes in later life, including longevity. Does it also predict how well people age? We studied the association between self-control and midlife aging in a population-representative cohort of children followed from birth to age 45 y, the Dunedin Study. We measured children’s self-control across their first decade of life using a multi-occasion/multiinformant strategy. We measured their pace of aging and aging preparedness in midlife using measures derived from biological and physiological assessments, structural brain-imaging scans, observer ratings, self-reports, informant reports, and administrative records. As adults, children with better self-control aged more slowly in their bodies and showed fewer signs of aging in their brains. By midlife, these children were also better equipped to manage a range of later-life health, financial, and social demands. Associations with children’s self-control could be separated from their social class origins and intelligence, indicating that self-control might be an active ingredient in healthy aging. Children also shifted naturally in their level of self-control across adult life, suggesting the possibility that self-control may be a malleable target for intervention. Furthermore, individuals’ self-control in adulthood was associated with their aging outcomes after accounting for their self-control in childhood, indicating that midlife might offer another window of opportunity to promote healthy aging.
KW - Aging
KW - Health span
KW - Longitudinal
KW - Self-control
KW - Self-regulation
UR - http://www.scopus.com/inward/record.url?scp=85099132659&partnerID=8YFLogxK
U2 - 10.1073/pnas.2010211118
DO - 10.1073/pnas.2010211118
M3 - Article
C2 - 33397808
AN - SCOPUS:85099132659
SN - 0027-8424
VL - 118
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 3
M1 - e2010211118
ER -