Chemical constituents and their antibacterial and antifungal activity from the Egyptian herbal medicine Chiliadenus montanus

Mohamed Elamir F. Hegazy, Hisashi Matsuda, Seikou Nakamura, Taha A. Hussein, Masayuki Yoshikawa, Paul W. Paré

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Phytochemical investigations of the CH2Cl2/MeOH (1:1) extract of air-dried aerial parts of Chiliadenus montanus afforded eight metabolites, in addition to eight other previously reported compounds, of which two were isolated for the first time as free acids. Structures were established by spectroscopic methods, including HREIMS, 1H, 13C, DEPT, 1H-1H COSY, HMQC and HMBC NMR analysis. Antimicrobial activity against an array of common bacterial and fungal strains was measured via a colorimetric assay with minimal growth inhibition observed in the μg/mL range for one of the tested metabolites.

Original languageEnglish
Pages (from-to)154-161
Number of pages8
JournalPhytochemistry
Volume103
DOIs
StatePublished - Jul 2014

Keywords

  • Antimicrobial activity
  • Asteraceae
  • Chiliadenus montanus
  • Dioxane
  • Flavonoids
  • Sesquiterpenes

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