Cell affinity separations on microfluidic devices

Yan Gao, Wenjie Li, Ye Zhang, Dimitri Pappas

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Separating cells from a heterogeneous sample on microfluidic devices is a very important unit operation in biological and medical research. Microfluidic affinity cell chromatography is a label-free separation technique, providing ease of operation, low cost, and rapid analysis. In this chapter, protocols for cell affinity separation in polydimethylsiloxane (PDMS)–glass microdevices and glass capillaries are described.

Original languageEnglish
Pages (from-to)55-65
Number of pages11
JournalMethods in Molecular Biology
Volume1286
DOIs
StatePublished - Jan 1 2015

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Keywords

  • Affinity chromatography
  • Cell separation
  • Glass capillaries
  • Microfluidic device
  • Polydimethylsiloxane

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