Abstract
A new copper-catalyzed sulfur-enabled dehydrobicyclization of 1,6-enynes
using potassium sulfide as a sulfurating reagent has been established,
providing a straightforward access toward arylated
indeno[1,2-c]thiophenes with moderate to good yields. This sulfur
incorporation pathway involves Michael addition, 5-exo-dig/S-endo-trig
bicyclization and dehydrogenation sequence, resulting in continuous
multiple bond-forming events including C-S and C-C bonds to rapidly
construct functional organic molecules.
Original language | English |
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Pages (from-to) | 4762-4770 |
Journal | Journal of Organic Chemistry |
State | Published - Jun 2016 |