TY - JOUR
T1 - Catalytic Sulfur-Enabled Dehydrobicyclization of 1,6-Enynes toward
Arylated Indeno[1,2-c]thiophenes
AU - Wu, Ya-Nan
AU - Fu, Rong
AU - Wang, Nan-Nan
AU - Hao, Wen-Juan
AU - Li, Guigen
AU - Tu, Shu-Jiang
AU - Jiang, Bo
PY - 2016/6
Y1 - 2016/6
N2 - A new copper-catalyzed sulfur-enabled dehydrobicyclization of 1,6-enynes
using potassium sulfide as a sulfurating reagent has been established,
providing a straightforward access toward arylated
indeno[1,2-c]thiophenes with moderate to good yields. This sulfur
incorporation pathway involves Michael addition, 5-exo-dig/S-endo-trig
bicyclization and dehydrogenation sequence, resulting in continuous
multiple bond-forming events including C-S and C-C bonds to rapidly
construct functional organic molecules.
AB - A new copper-catalyzed sulfur-enabled dehydrobicyclization of 1,6-enynes
using potassium sulfide as a sulfurating reagent has been established,
providing a straightforward access toward arylated
indeno[1,2-c]thiophenes with moderate to good yields. This sulfur
incorporation pathway involves Michael addition, 5-exo-dig/S-endo-trig
bicyclization and dehydrogenation sequence, resulting in continuous
multiple bond-forming events including C-S and C-C bonds to rapidly
construct functional organic molecules.
M3 - Article
SP - 4762
EP - 4770
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
SN - 0022-3263
ER -