Abstract
Chemical equations presented. A catalytic asymmetric addition of arylboronic acids to isatins has been achieved by using chiral cationic C 2-symmetric N-heterocyclic carbene (NHC) Pd2+ diaqua complexes as the catalysts. The reaction can be performed under convenient conditions to give the corresponding adducts in good to high yields (79-94%) and moderate to excellent enantioselectivities (up to 94% ee) in the presence of LiOAr as the promoter which was generated in situ.
Original language | English |
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Pages (from-to) | 2314-2317 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 13 |
Issue number | 9 |
DOIs | |
State | Published - May 6 2011 |