Casbane diterpenes from Red Sea Coral Sinularia polydactyla

Mohamed Elamir F. Hegazy, Tarik A. Mohamed, Abdelsamed I. Elshamy, Montaser A. Al-Hammady, Shinji Ohta, Paul W. Paré

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4-5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis.

Original languageEnglish
Article number308
Issue number3
StatePublished - Mar 2016


  • Alcyoniidae
  • Diterpenes
  • Sinularia polydactyla
  • Soft coral


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