Carbon-13 nmr studies on sitosterol biosynthesized from [13C]mevalonates

W. David Nes, Robert A. Norton, Mabry Benson

Research output: Contribution to journalArticlepeer-review

73 Scopus citations


[2-13C]Mevalonic acid and [5-13C]mevalonic acid were fed to cultured cells of sunflower and the resulting biosynthesized [13C]sitosterols were examined by 13C NMR spectroscopy. The observations confirmed the biochemically predictable positions of 13C labels in sitosterol. Based on the new information a mechanism for the biogenesis of the C-24 alkyl group in phytosterols is given.

Original languageEnglish
Pages (from-to)805-811
Number of pages7
Issue number3
StatePublished - Mar 1992


  • Compositae
  • Helianthus annus
  • mechanism of C-24 alkylation.
  • sterol biosynthesis


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