Carbon-13 nmr studies on sitosterol biosynthesized from [13C]mevalonates

W. David Nes; Robert A. Norton; Mabry Benson

doi:10.1016/0031-9422(92)80019-B

Carbon-13 nmr studies on sitosterol biosynthesized from [¹³C]mevalonates

W. David Nes, Robert A. Norton, Mabry Benson

Chemistry and Biochemistry

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73 Scopus citations

Abstract

[2-¹³C]Mevalonic acid and [5-¹³C]mevalonic acid were fed to cultured cells of sunflower and the resulting biosynthesized [¹³C]sitosterols were examined by ¹³C NMR spectroscopy. The observations confirmed the biochemically predictable positions of ¹³C labels in sitosterol. Based on the new information a mechanism for the biogenesis of the C-24 alkyl group in phytosterols is given.

Original language	English
Pages (from-to)	805-811
Number of pages	7
Journal	Phytochemistry
Volume	31
Issue number	3
DOIs	https://doi.org/10.1016/0031-9422(92)80019-B
State	Published - Mar 1992

Keywords

Compositae
Helianthus annus
mechanism of C-24 alkylation.
sterol biosynthesis

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10.1016/0031-9422(92)80019-B

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title = "Carbon-13 nmr studies on sitosterol biosynthesized from [13C]mevalonates",

abstract = "[2-13C]Mevalonic acid and [5-13C]mevalonic acid were fed to cultured cells of sunflower and the resulting biosynthesized [13C]sitosterols were examined by 13C NMR spectroscopy. The observations confirmed the biochemically predictable positions of 13C labels in sitosterol. Based on the new information a mechanism for the biogenesis of the C-24 alkyl group in phytosterols is given.",

keywords = "Compositae, Helianthus annus, mechanism of C-24 alkylation., sterol biosynthesis",

author = "Nes, {W. David} and Norton, {Robert A.} and Mabry Benson",

year = "1992",

month = mar,

doi = "10.1016/0031-9422(92)80019-B",

language = "English",

volume = "31",

pages = "805--811",

journal = "Phytochemistry",

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T1 - Carbon-13 nmr studies on sitosterol biosynthesized from [13C]mevalonates

AU - Nes, W. David

AU - Norton, Robert A.

AU - Benson, Mabry

PY - 1992/3

Y1 - 1992/3

N2 - [2-13C]Mevalonic acid and [5-13C]mevalonic acid were fed to cultured cells of sunflower and the resulting biosynthesized [13C]sitosterols were examined by 13C NMR spectroscopy. The observations confirmed the biochemically predictable positions of 13C labels in sitosterol. Based on the new information a mechanism for the biogenesis of the C-24 alkyl group in phytosterols is given.

AB - [2-13C]Mevalonic acid and [5-13C]mevalonic acid were fed to cultured cells of sunflower and the resulting biosynthesized [13C]sitosterols were examined by 13C NMR spectroscopy. The observations confirmed the biochemically predictable positions of 13C labels in sitosterol. Based on the new information a mechanism for the biogenesis of the C-24 alkyl group in phytosterols is given.

KW - Compositae

KW - Helianthus annus

KW - mechanism of C-24 alkylation.

KW - sterol biosynthesis

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U2 - 10.1016/0031-9422(92)80019-B

DO - 10.1016/0031-9422(92)80019-B

M3 - Article

AN - SCOPUS:0001240529

SN - 0031-9422

VL - 31

SP - 805

EP - 811

JO - Phytochemistry

JF - Phytochemistry

IS - 3

ER -

Carbon-13 nmr studies on sitosterol biosynthesized from [¹³C]mevalonates

Abstract

Keywords

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