Calf exercise-induced vasodilation is blunted in healthy older adults with increased walking performance fatigue

Joaquin Gonzales, Elizabeth Defferari, Amy Fisher, Jordan Shephard, David N. Proctor

Research output: Contribution to journalArticle

Abstract

Walking speed decreases progressively with advancing age due to physiological mechanisms that are not fully understood. Vascular aging as measured by central arterial stiffness contributes to slow walking speed in older adults, but the impact of age-related changes in peripheral vascular function on walking performance is unclear. The aim of this study was to test the hypothesis that calf muscle-specific vasodilator responses are associated with walking performance fatigue in healthy older adults (N=45, 60-78 yrs). Peak calf vascular conductance was measured following 10 min of arterial occlusion using strain-gauge plethysmography. Superficial femoral artery (SFA) vascular conductance response to graded plantar-flexion exercise was measured using Doppler ultrasound. Walking fatigue was defined as an inability to sustain walking speed during a 400m walk test (2 min vs. overall 400m speed). No difference was found for peak calf vascular conductance between walking performance grou
Original languageEnglish
Pages (from-to)1-5
JournalExperimental Gerontology
StatePublished - May 12 2014

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