Caenorhabditis elegans senses bacterial autoinducers

Elmus Beale, Guigen Li, Man Wah Tan, Kendra P. Rumbaugh

Research output: Contribution to journalArticlepeer-review

86 Scopus citations


Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans. Here we show that C. elegans is attracted to the acylated homoserine lactones (AHSLs) that mediate QS in P. aeruginosa. Our data also indicate that C. elegans can distinguish AHSLs and may use them to mediate aversive or attractive learning.

Original languageEnglish
Pages (from-to)5135-5137
Number of pages3
JournalApplied and environmental microbiology
Issue number7
StatePublished - Jul 2006


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