Caenorhabditis elegans senses bacterial autoinducers

Elmus Beale; Guigen Li; Man Wah Tan; Kendra P. Rumbaugh

doi:10.1128/AEM.00611-06

Caenorhabditis elegans senses bacterial autoinducers

Elmus Beale, Guigen Li, Man Wah Tan, Kendra P. Rumbaugh

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans. Here we show that C. elegans is attracted to the acylated homoserine lactones (AHSLs) that mediate QS in P. aeruginosa. Our data also indicate that C. elegans can distinguish AHSLs and may use them to mediate aversive or attractive learning.

Original language	English
Pages (from-to)	5135-5137
Number of pages	3
Journal	Applied and environmental microbiology
Volume	72
Issue number	7
DOIs	https://doi.org/10.1128/AEM.00611-06
State	Published - Jul 2006

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title = "Caenorhabditis elegans senses bacterial autoinducers",

abstract = "Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans. Here we show that C. elegans is attracted to the acylated homoserine lactones (AHSLs) that mediate QS in P. aeruginosa. Our data also indicate that C. elegans can distinguish AHSLs and may use them to mediate aversive or attractive learning.",

author = "Elmus Beale and Guigen Li and Tan, {Man Wah} and Rumbaugh, {Kendra P.}",

year = "2006",

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AU - Beale, Elmus

AU - Li, Guigen

AU - Tan, Man Wah

AU - Rumbaugh, Kendra P.

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Y1 - 2006/7

N2 - Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans. Here we show that C. elegans is attracted to the acylated homoserine lactones (AHSLs) that mediate QS in P. aeruginosa. Our data also indicate that C. elegans can distinguish AHSLs and may use them to mediate aversive or attractive learning.

AB - Pseudomonas aeruginosa uses virulence factors controlled by quorum sensing (QS) to kill Caenorhabditis elegans. Here we show that C. elegans is attracted to the acylated homoserine lactones (AHSLs) that mediate QS in P. aeruginosa. Our data also indicate that C. elegans can distinguish AHSLs and may use them to mediate aversive or attractive learning.

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M3 - Article

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AN - SCOPUS:33746094661

VL - 72

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EP - 5137

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

SN - 0099-2240

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ER -

Caenorhabditis elegans senses bacterial autoinducers

Abstract

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