Benzisothiazol-3-ones through a Metal-Free Intramolecular N–S Bond Formation

Ke Yang, Hao Zhang, Ben Niu, Tiandi Tang, Haibo Ge

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The highly efficient synthesis of benzoisothiazol-3-ones from thiobenzamides has been described with good functional group compatibility and excellent yields. This work represents the first example of selectfluor-promoted N–S bond formation processes. This method provides a facile approach to access various important bioactive benzoisothiazol-3-ones.

Original languageEnglish
Pages (from-to)5520-5523
Number of pages4
JournalEuropean Journal of Organic Chemistry
Issue number40
StatePublished - Nov 1 2018


  • Cleavage reactions
  • Cyclization
  • Selectfluor
  • Sulfur heterocycles
  • Synthetic methods


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