Attenuated aortic blood pressure responses to metaboreflex activation in older adults with dynapenia

Arturo Figueroa-Galvez, Alexei Wong, Salvador J. Jaime, Brandon Grubbs, Lynn B. Panton, Stephen M. Fischer

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

<b>Background: </b>Low muscle strength (dynapenia) is a primary characteristic of sarcopenia, the age-related loss of muscle mass and strength or low walking speed. New evidence suggests that muscle strength positively affects blood pressure (BP) responses to exercise. As older adults with lowest handgrip strength also have lowest BP at rest, those with dynapenia may experience attenuated BP responses during physical activity. The purpose of this study was to test the hypothesis that dynapenic older adults would exhibit lower BP response to post-exercise muscle ischemia (PEMI).<br><b>Methods: </b>Brachial and aortic systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were measured in older adults (age, 80 ± 5 y) with dynapenia (n = 16) and non-dynapenia (n = 9) at rest and during PEMI following 2 min of isometric handgrip exercise at 30% maximal voluntary contraction. Walking speed was assessed by an 8-foot (2.44 m) walk course.<br><b>Results: </b>Increases in aort
Original languageEnglish
Article number110984
JournalExperimental Gerontology
Volume138
DOIs
StatePublished - Sep 2020

Keywords

  • Aging
  • Diastolic pressure
  • Handgrip strength
  • Post-exercise muscle ischemia
  • Walking performance

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