Attenuated aortic blood pressure responses to metaboreflex activation in older adults with dynapenia

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Abstract

<b>Background: </b>Low muscle strength (dynapenia) is a primary characteristic of sarcopenia, the age-related loss of muscle mass and strength or low walking speed. New evidence suggests that muscle strength positively affects blood pressure (BP) responses to exercise. As older adults with lowest handgrip strength also have lowest BP at rest, those with dynapenia may experience attenuated BP responses during physical activity. The purpose of this study was to test the hypothesis that dynapenic older adults would exhibit lower BP response to post-exercise muscle ischemia (PEMI).<br><b>Methods: </b>Brachial and aortic systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were measured in older adults (age, 80 ± 5 y) with dynapenia (n = 16) and non-dynapenia (n = 9) at rest and during PEMI following 2 min of isometric handgrip exercise at 30% maximal voluntary contraction. Walking speed was assessed by an 8-foot (2.44 m) walk course.<br><b>Results: </b>Increases in aort
Original languageEnglish
JournalExperimental Gerontology
StatePublished - Sep 2020

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