@article{d9bc03a51417437ba2d3fb52d7150aba,
title = "Asymmetric synthesis of β′-amino-α,β-enones via addition of α,β-unsaturated ketone-derived enolates to chiral N-phosphonyl imines",
abstract = "Efficient asymmetric Mannich addition reactions between α,β-unsaturated ketone derived enolates and N-phosphonyl imines were reported. These reactions could proceed smoothly for a variety of imine substrates with good (up to 96%) chemical yields and excellent diastereoselectivities (up to 98:2 dr). The method reported in this work provides an easy access to chiral β′-amino-α,β-enones.",
keywords = "Asymmetric Mannich reaction, Diastereoselectivity, N-Phosphonyl imine, α,β-Unsaturated ketone, β′-Amino-α,β-enones",
author = "Yiwen Xiong and Haibo Mei and Jianlin Han and Guigen Li and Yi Pan",
note = "Funding Information: We gratefully acknowledge the financial support from the National Natural Science Foundation of China (No. 21102071 ) and the Fundamental Research Funds for the Central Universities (Nos. 1107020522 and 1082020502 ). The Jiangsu 333 program (for Pan) and Changzhou Jin-Feng-Huang program (for Han) are also acknowledged. ",
year = "2014",
month = apr,
day = "9",
doi = "10.1016/j.tetlet.2014.03.005",
language = "English",
volume = "55",
pages = "2476--2479",
journal = "Tetrahedron Letters",
issn = "0040-4039",
number = "15",
}