Arterial stiffness is higher in older adults with increased perceived fatigue and fatigability during walking

Joaquin Gonzales, Matthew Wiberg, Elizabeth Defferari, David N. Proctor

Research output: Contribution to journalArticle

Abstract

We investigated whether central and/or peripheral arterial stiffness contributes to increased perceived fatigue during walking in mobility-intact older adults. Arterial stiffness of the common carotid artery and superficial femoral artery (SFA) was measured using Doppler-ultrasound in 45 community-dwelling women and men. The change in perceived fatigue was measured after a fast-pace 400 meter walk test. Adults that rated feeling more tired after walking (n=10) had higher SFA stiffness (p<0.05), but not carotid stiffness, than adults that reported feeling more energetic after walking (n=22). The perceived fatigue rating was normalized to energy expenditure during walking to determine fatigability. Adults were divided into tertiles (n=15) based on the fatigability score. Carotid and SFA stiffness was elevated in the highest fatigability tertile as compared to the lowest tertile (p<0.05). After adjusting for age, sex, body fat, mean blood pressure, daily physical activity levels,
Original languageEnglish
Pages (from-to)92-97
JournalExperimental Gerontology
StatePublished - Jan 1 2015

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