Abstract
The first example of constructing a C sp3 -C sp bond with substituted Hantzsch ester and Meyer nitrile is reported. When benziodoxole-activated alkyne was applied as the alkynyl donor, products containing C sp3 -C sp bonds involving primary, secondary, and tertiary carbon centers were achieved in up to 97% yields. K 2 S 2 O 8 was the optimum radical initiator in this reaction.
Original language | English |
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Pages (from-to) | 6906-6909 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 20 |
Issue number | 21 |
DOIs | |
State | Published - Nov 2 2018 |