@article{09a0a9d4c10746279b939e73dad8ecea,
title = "Application of Hantzsch Ester and Meyer Nitrile in Radical Alkynylation Reactions",
abstract = " The first example of constructing a C sp3 -C sp bond with substituted Hantzsch ester and Meyer nitrile is reported. When benziodoxole-activated alkyne was applied as the alkynyl donor, products containing C sp3 -C sp bonds involving primary, secondary, and tertiary carbon centers were achieved in up to 97% yields. K 2 S 2 O 8 was the optimum radical initiator in this reaction. ",
author = "Xu Liu and Ruoyu Liu and Jie Dai and Xu Cheng and Guigen Li",
note = "Funding Information: This work was supported by the National Science Foundation of China (Nos. 21572099 and 21332005) and the Natural Science Foundation of Jiangsu Province (No. BK20151379). This study was supported by the Open Project of State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine (Nos. TCMQ and E 201702). R.L. and J.D. appreciate the open training program of the undergraduate organic experiment course (0205145031-6) . Publisher Copyright: Copyright {\textcopyright} 2018 American Chemical Society.",
year = "2018",
month = nov,
day = "2",
doi = "10.1021/acs.orglett.8b03050",
language = "English",
volume = "20",
pages = "6906--6909",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society (ACS)",
number = "21",
}