Annulus tension of the prolapsed mitral valve corrected by edge-to-edge repair

Shamik Bhattacharya, Zhaoming He

Research output: Contribution to journalArticlepeer-review


Background: Mitral valve (MV) performance after edge-to-edge repair (ETER) without ring annuloplasty is suboptimal. ETER efficacy needs to be evaluated from annulus tension (AT) of a prolapsed MV corrected by ETER to understand annular dilatation. Methods: Ten porcine MVs were harvested and mounted on a MV closure test rig. The MV annulus tissue rested on top of a saddle-shaped plastic ring on which the annulus could slide freely. The annulus was held by strings in the periphery during MV closure under a hydrostatic trans-mitral pressure. String tensions were measured and further divided by string spacing to obtain AT. The MVs were then prolapsed by shifting split papillary muscles to simulate mono-leaflet prolapse due to elongation of chords which insert into a single leaflet. Last, MV prolapse was corrected by ETER applied in the central leaflet region and AT was measured. Results: AT in both anterior and posterior leaflet prolapse corrected by ETER was less than that of normal M
Original languageEnglish
Pages (from-to)1-7
JournalJournal of Biomechanics
StatePublished - Jan 2012


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