Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels

Yi Quan Tang, Sol Ah Lee, Mizanur Rahman, Siva A. Vanapalli, Hang Lu, William R. Schafer

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

TMC channels are important for sensory transduction, notably as key components of the hair cell mechanotransducer. In this issue of Neuron, Tang et al. show that the mechanosensory activity of C. elegans TMCs requires the intracellular tether ankyrin, which interacts with TMC-1 through the adaptor protein CALM-1.

Original languageEnglish
Pages (from-to)112-125.e10
JournalNeuron
Volume107
Issue number1
DOIs
StatePublished - Jul 8 2020

Keywords

  • C. elegans
  • CIB
  • TMC
  • ankyrin
  • gating spring
  • hair cells
  • mechanotransduction channel
  • nose touch
  • tether

Fingerprint Dive into the research topics of 'Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels'. Together they form a unique fingerprint.

Cite this