TY - JOUR
T1 - An investigation of short-term longitudinal associations between handgrip strength and cardiovascular disease biomarkers among middle-aged to older adults
T2 - A project frontier study
AU - Kim, Youngdeok
AU - Gonzales, Joaquin U.
AU - Hemachandra Reddy, P.
N1 - Funding Information:
The authors sincerely thank all the study participants of Project FRONTIER. Project FRONTIER is supported by the Garrison Institute of Aging at Texas Tech University Health Science Center, Lubbock, TX, USA. P.H. Reddy is supported by NIH R01 grants AG042178, AG047812, and NS105473; the Garrison Family Foundation; the CH Foundation; and the Alzheimer?s Association SAGA grant. The sponsor had no role in the design, methods, subject recruitment, data collections, analysis, or preparation of paper. The authors declare that they have no conflict of interest.
Funding Information:
The authors sincerely thank all the study participants of Project FRONTIER. Project FRONTIER is supported by the Garrison Institute of Aging at Texas Tech University Health Science Center, Lubbock, TX, USA. P.H. Reddy is supported by NIH R01 grants AG042178, AG047812, and NS105473; the Garrison Family Foundation; the CH Foundation; and the Alzheimer’s Association SAGA grant. The sponsor had no role in the design, methods, subject recruitment, data collections, analysis, or preparation of paper. The authors declare that they have no conflict of interest.
Publisher Copyright:
© 2020 Human Kinetics, Inc.
PY - 2020
Y1 - 2020
N2 - The purpose of this study was to examine short-term longitudinal relationships between handgrip strength (HGS) and cardiovascular disease (CVD) biomarkers in middle-aged to older adults living in rural areas (N = 138). The association between HGS and CVD biomarkers was examined at baseline, with HGS as a predictor of the annual change in biomarkers, and in a parallel fashion between the annual change in HGS and CVD biomarkers over an average of 2.8 follow-up years. The results showed HGS to cross-sectionally associate with waist circumference and diastolic blood pressure at baseline, but HGS at baseline was not found to predict the annual change in any biomarker. The annual increase in HGS was significantly associated with favorable changes in high-density lipoprotein cholesterol, triglycerides, and systolic/diastolic blood pressures; yet, these associations varied by the baseline levels of biomarkers. The present findings suggest that improved muscle strength with aging is related to favorable changes in CVD biomarkers.
AB - The purpose of this study was to examine short-term longitudinal relationships between handgrip strength (HGS) and cardiovascular disease (CVD) biomarkers in middle-aged to older adults living in rural areas (N = 138). The association between HGS and CVD biomarkers was examined at baseline, with HGS as a predictor of the annual change in biomarkers, and in a parallel fashion between the annual change in HGS and CVD biomarkers over an average of 2.8 follow-up years. The results showed HGS to cross-sectionally associate with waist circumference and diastolic blood pressure at baseline, but HGS at baseline was not found to predict the annual change in any biomarker. The annual increase in HGS was significantly associated with favorable changes in high-density lipoprotein cholesterol, triglycerides, and systolic/diastolic blood pressures; yet, these associations varied by the baseline levels of biomarkers. The present findings suggest that improved muscle strength with aging is related to favorable changes in CVD biomarkers.
KW - CVD
KW - Metabolic syndrome
KW - Muscular strength
KW - Physical activity
KW - Prospective cohort
UR - http://www.scopus.com/inward/record.url?scp=85083792920&partnerID=8YFLogxK
U2 - 10.1123/japa.2018-0399
DO - 10.1123/japa.2018-0399
M3 - Article
C2 - 31141435
AN - SCOPUS:85083792920
VL - 28
SP - 9
EP - 17
JO - Journal of Aging and Physical Activity
JF - Journal of Aging and Physical Activity
SN - 1063-8652
IS - 1
ER -