TY - JOUR
T1 - An elongation model of left ventricle deformation in diastole
AU - Hu, Yingying
AU - Shi, Liang
AU - Du, Dongxing
AU - Parameswaran, Siva
AU - He, Zhaoming
N1 - Funding Information:
This study was supported by an Exploratory/Developmental Research Grant Award from the National Heart, Lung, and Blood Institute (grant No. R21HL102526).
PY - 2013/1/22
Y1 - 2013/1/22
N2 - A numerical method of the left ventricle (LV) deformation, an elongation model, was put forth for the study of LV fluid mechanics in diastole. The LV elongated only along the apical axis, and the motion was controlled by the intraventricular flow rate. Two other LV models, a fixed control volume model and a dilation model, were also used for model comparison and the study of LV fluid mechanics. For clinical sphere indices (SIs, between 1.0 and 2.0), the three models showed little difference in pressure and velocity distributions along the apical axis at E-peak. The energy dissipation was lower at a larger SI in that the jet and vortex development was less limited by the LV cavity in the apical direction. LV deformation of apical elongation may represent the primary feature of LV deformation in comparison with the secondary radial expansion. The elongation model of the LV deformation with an appropriate SI is a reasonable, simple method to study LV fluid mechanics in diastole.
AB - A numerical method of the left ventricle (LV) deformation, an elongation model, was put forth for the study of LV fluid mechanics in diastole. The LV elongated only along the apical axis, and the motion was controlled by the intraventricular flow rate. Two other LV models, a fixed control volume model and a dilation model, were also used for model comparison and the study of LV fluid mechanics. For clinical sphere indices (SIs, between 1.0 and 2.0), the three models showed little difference in pressure and velocity distributions along the apical axis at E-peak. The energy dissipation was lower at a larger SI in that the jet and vortex development was less limited by the LV cavity in the apical direction. LV deformation of apical elongation may represent the primary feature of LV deformation in comparison with the secondary radial expansion. The elongation model of the LV deformation with an appropriate SI is a reasonable, simple method to study LV fluid mechanics in diastole.
KW - diastole
KW - elongation
KW - left ventricle deformation
KW - prolate spheroid
UR - http://www.scopus.com/inward/record.url?scp=84872526121&partnerID=8YFLogxK
U2 - 10.1080/10255842.2011.607442
DO - 10.1080/10255842.2011.607442
M3 - Article
AN - SCOPUS:84872526121
SN - 1025-5842
VL - 16
SP - 66
EP - 72
JO - Computer Methods in Biomechanics and Biomedical Engineering
JF - Computer Methods in Biomechanics and Biomedical Engineering
IS - 1
ER -