Alterations in the Physiology of Growth of Cattle with Growth-Enhancing Compounds

Bradley J. Johnson, Ki Yong Chung

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Commonly used growth promotants such as steroidal implants and β-adrenergic agonists have recently been implicated in the reduction of marbling scores in beef cattle. These compounds are effective at improving lean tissue deposition in cattle, thus significantly improving feed efficiency. This article discusses skeletal muscle growth and development in cattle, the process of transdifferentiation between two cell types, and how growth promotants may push a nondifferentiated cell to become a certain lineage of cells. Increased understanding of how these agents affect cellular aspects of growth and development of skeletal muscle and adipose tissue will allow cattle feeders, consultants, and researchers to instigate intervention strategies to ameliorate the reduced marbling scores. Successful strategies would allow maximal lean tissue growth and result in carcasses with optimal quality.

Original languageEnglish
Pages (from-to)321-332
Number of pages12
JournalVeterinary Clinics of North America - Food Animal Practice
Issue number2
StatePublished - Jul 2007


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