A translocated mitochondrial cytochrome b pseudogene in voles (Rodentia: Microtus)

J. A. DeWoody; R. K. Chesser; R. J. Baker

doi:10.1007/PL00013154

A translocated mitochondrial cytochrome b pseudogene in voles (Rodentia: Microtus)

J. A. DeWoody, R. K. Chesser, R. J. Baker

Biological Sciences

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48 Scopus citations

Abstract

A full-length cytochrome b pseudogene was found in rodents; it has apparently been translocated from a mitochondrion to the nuclear genome in the subfamily Arvicolinae. The pseudogene (ψcytb) differed from its mitochondrial counterpart at 201 of 1143 sites (17.6%) and by four indels. Cumulative evidence suggests that the pseudogene has been translocated to the nucleus. Phylogenetic reconstruction indicates that the pseudogene arose before the diversification of M. arvalis/M. rossiaemeridionalis from M. oeconomus, but after the divergence of the peromyscine/sigmodontine/arvicoline clades some ~10 MYA. Published rates of divergence between mitochondrial genes and their nuclear pseudogenes suggest that the translocation of this mitochondrial gene to the nuclear genome occurred some 6 MYA, in agreement with the phylogenetic evidence.

Original language	English
Pages (from-to)	380-382
Number of pages	3
Journal	Journal of Molecular Evolution
Volume	48
Issue number	3
DOIs	https://doi.org/10.1007/PL00013154
State	Published - 1999

Keywords

Cytochrome b
Microtus
MtDNA
Pseudogene
Rodent
Translocation

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10.1007/PL00013154

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title = "A translocated mitochondrial cytochrome b pseudogene in voles (Rodentia: Microtus)",

abstract = "A full-length cytochrome b pseudogene was found in rodents; it has apparently been translocated from a mitochondrion to the nuclear genome in the subfamily Arvicolinae. The pseudogene (ψcytb) differed from its mitochondrial counterpart at 201 of 1143 sites (17.6%) and by four indels. Cumulative evidence suggests that the pseudogene has been translocated to the nucleus. Phylogenetic reconstruction indicates that the pseudogene arose before the diversification of M. arvalis/M. rossiaemeridionalis from M. oeconomus, but after the divergence of the peromyscine/sigmodontine/arvicoline clades some ~10 MYA. Published rates of divergence between mitochondrial genes and their nuclear pseudogenes suggest that the translocation of this mitochondrial gene to the nuclear genome occurred some 6 MYA, in agreement with the phylogenetic evidence.",

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T1 - A translocated mitochondrial cytochrome b pseudogene in voles (Rodentia: Microtus)

AU - DeWoody, J. A.

AU - Chesser, R. K.

AU - Baker, R. J.

PY - 1999

Y1 - 1999

N2 - A full-length cytochrome b pseudogene was found in rodents; it has apparently been translocated from a mitochondrion to the nuclear genome in the subfamily Arvicolinae. The pseudogene (ψcytb) differed from its mitochondrial counterpart at 201 of 1143 sites (17.6%) and by four indels. Cumulative evidence suggests that the pseudogene has been translocated to the nucleus. Phylogenetic reconstruction indicates that the pseudogene arose before the diversification of M. arvalis/M. rossiaemeridionalis from M. oeconomus, but after the divergence of the peromyscine/sigmodontine/arvicoline clades some ~10 MYA. Published rates of divergence between mitochondrial genes and their nuclear pseudogenes suggest that the translocation of this mitochondrial gene to the nuclear genome occurred some 6 MYA, in agreement with the phylogenetic evidence.

AB - A full-length cytochrome b pseudogene was found in rodents; it has apparently been translocated from a mitochondrion to the nuclear genome in the subfamily Arvicolinae. The pseudogene (ψcytb) differed from its mitochondrial counterpart at 201 of 1143 sites (17.6%) and by four indels. Cumulative evidence suggests that the pseudogene has been translocated to the nucleus. Phylogenetic reconstruction indicates that the pseudogene arose before the diversification of M. arvalis/M. rossiaemeridionalis from M. oeconomus, but after the divergence of the peromyscine/sigmodontine/arvicoline clades some ~10 MYA. Published rates of divergence between mitochondrial genes and their nuclear pseudogenes suggest that the translocation of this mitochondrial gene to the nuclear genome occurred some 6 MYA, in agreement with the phylogenetic evidence.

KW - Cytochrome b

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KW - MtDNA

KW - Pseudogene

KW - Rodent

KW - Translocation

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A translocated mitochondrial cytochrome b pseudogene in voles (Rodentia: Microtus)

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Keywords

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