A study on perchlorate exposure and absorption in beef cattle

Qiuqiong Cheng, Lisa Perlmutter, Philip N. Smith, Scott T. McMurry, William A. Jackson, Todd A. Anderson

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Perchlorate exposure and potential effects were evaluated in large mammals by monitoring heifer calves placed on a site with access to streamwater fed by a perchlorate-contaminated groundwater spring (∼25 ng/mL). Blood was collected from the two calves on the site (and two control calves from an uncontaminated site) approximately every 2 weeks for analysis of perchlorate residues and thyroid hormones. During the 14 week study, perchlorate was detected (detection limit = 13.7 ng/mL) in blood plasma twice (15 ng/mL and 22 ng/mL) in one of the heifer calves drinking perchlorate-contaminated water on consecutive sampling periods 4 and 6 weeks after the beginning of perchlorate exposure. Constant exposure to 25 ppb perchlorate in drinking water had no effect on circulating thyroid hormones (T3 and T4) in the heifer calves.

Original languageEnglish
Pages (from-to)3456-3461
Number of pages6
JournalJournal of Agricultural and Food Chemistry
Volume52
Issue number11
DOIs
StatePublished - Jun 2 2004

Keywords

  • Blood
  • Cattle
  • Ion chromatography
  • Perchlorate
  • Thyroid hormones

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