A simple and convenient method for the synthesis of N, N-diaryl tertiary amines

Francis Wekesa, Neha Phadke, Claire Jahier, David B. Cordes, Michael Findlater

Research output: Contribution to journalArticlepeer-review

Abstract

Direct preparation of tertiary amines in which two substituents are aromatic is described. In the presence of either the inorganic base sodium tert-butoxide or the sterically hindered organic base diisopropylethylamine, the alkylation of secondary diarylamines is achieved smoothly. In contrast to methods previously reported in the literature, this procedure is high-yielding and does not require the use of transition-metal catalysts or functional-group-intolerant hydride reductants. © Georg Thieme Verlag Stuttgart • New York.
Original languageEnglish
Pages (from-to)1046-1051
JournalSynthesis (Germany)
StatePublished - Jan 1 2014

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