A review of emerging industrial and systems engineering trends and future directions in biomanufacturing

Zhuo Tan, Rohan A. Shirwaiker

Research output: Contribution to conferencePaperpeer-review


Biomanufacturing is an evolving area of interdisciplinary research that bridges physical, biological and engineering sciences to create commercially viable and sustainable life sciences-based products and systems. As such, its definitions and descriptions vary across disciplines. This paper takes a broad view of recent biomanufacturing literature and attempts to classify and explore aspects that are critical from an industrial and systems engineering (ISE) perspective. The primary objectives of this review are to (a) outline multidisciplinary definitions and the scope of biomanufacturing, (b) assess the current state of art of biomanufacturing and its aspects with an ISE focus on, and (c) identify potential opportunities and challenges in realizing its potential economic benefits, in order to provide a basis for future ISE research in this area. The review suggests systems integration and flexibility as two emerging trends critical to the continued development and commercial success of the biomanufacturing industry.

Original languageEnglish
Number of pages8
StatePublished - 2012
Event62nd IIE Annual Conference and Expo 2012 - Orlando, FL, United States
Duration: May 19 2012May 23 2012


Conference62nd IIE Annual Conference and Expo 2012
Country/TerritoryUnited States
CityOrlando, FL


  • Biomanufacturing
  • Flexible manufacturing
  • Lean manufacturing
  • Scientific work flow
  • Systems engineering


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