TY - JOUR
T1 - A Purported Detoxification Supplement Does Not Improve Body Composition, Waist Circumference, Blood Markers, or Gastrointestinal Symptoms in Healthy Adult Females
AU - Tinsley, Grant
AU - Urbina, Stacie
AU - Santos, Emily
AU - Villa, Katelyn
AU - Foster, Cliffa
AU - Wilborn, Colin
AU - Taylor, Lem
N1 - Funding Information:
This study was funded by an external grant awarded to the investigators of the Human Performance Lab at the University of Mary Hardin-Baylor by MusclePharm and the International Society of Sports Nutrition. All testing was conducted in the Human Performance Lab in the Exercise & Sports Science department at the University of Mary Hardin-Baylor. We thank all participants, lab assistants, volunteers, sponsors, and student workers involved in this study.
Publisher Copyright:
© 2018, © 2018 Taylor & Francis Group, LLC.
PY - 2019/11/2
Y1 - 2019/11/2
N2 - Numerous popular “detoxification” supplements claim to promote the removal of harmful compounds from the body, thereby alleviating gastrointestinal symptoms, improving body composition, and enhancing overall health. The present double-blind, randomized, placebo-controlled trial was conducted to examine the effects of a purported detoxification supplement in healthy young adult females. Participants were randomly assigned to consume a multi-ingredient supplement or placebo daily for four weeks. The supplement contained 1,350 mg/serving of a proprietary blend of papaya leaf, cascara sagrada bark, slippery elm bark, peppermint leaf, red raspberry leaf, fenugreek seed, ginger root, and senna leaf. Body composition, waist circumferences, symptoms of gastrointestinal distress, and blood safety markers were evaluated before and after supplementation. Twenty-two participants completed the study, and data were analyzed via two-way mixed ANOVA and t tests. No beneficial or harmful effects of supplementation were found for body composition, waist circumference, gastrointestinal symptoms, or blood markers. These results indicate that consuming a commercially available dietary supplement that purportedly provides detoxification and body composition benefits is apparently safe in healthy young adult females but does not provide any beneficial effects for body composition or gastrointestinal symptoms.
AB - Numerous popular “detoxification” supplements claim to promote the removal of harmful compounds from the body, thereby alleviating gastrointestinal symptoms, improving body composition, and enhancing overall health. The present double-blind, randomized, placebo-controlled trial was conducted to examine the effects of a purported detoxification supplement in healthy young adult females. Participants were randomly assigned to consume a multi-ingredient supplement or placebo daily for four weeks. The supplement contained 1,350 mg/serving of a proprietary blend of papaya leaf, cascara sagrada bark, slippery elm bark, peppermint leaf, red raspberry leaf, fenugreek seed, ginger root, and senna leaf. Body composition, waist circumferences, symptoms of gastrointestinal distress, and blood safety markers were evaluated before and after supplementation. Twenty-two participants completed the study, and data were analyzed via two-way mixed ANOVA and t tests. No beneficial or harmful effects of supplementation were found for body composition, waist circumference, gastrointestinal symptoms, or blood markers. These results indicate that consuming a commercially available dietary supplement that purportedly provides detoxification and body composition benefits is apparently safe in healthy young adult females but does not provide any beneficial effects for body composition or gastrointestinal symptoms.
KW - botanical
KW - detoxification
KW - papaya
KW - peppermint
KW - slippery elm
UR - http://www.scopus.com/inward/record.url?scp=85049223644&partnerID=8YFLogxK
U2 - 10.1080/19390211.2018.1472713
DO - 10.1080/19390211.2018.1472713
M3 - Article
AN - SCOPUS:85049223644
SN - 1939-0211
VL - 16
SP - 649
EP - 658
JO - Journal of Dietary Supplements
JF - Journal of Dietary Supplements
IS - 6
ER -