@inproceedings{4bf34077851a44e5aaef5be7926b1b17,
title = "A novel approach for tumor sensitivity prediction and combination therapy design for targeted drugs",
abstract = "Drugs that target specific kinases are becoming common in cancer research. Cancer-related kinases are the paradigm of molecularly-targeted therapies, and a cornerstone of Personalized Cancer Therapy. Here, we present an approach to generate abstract circuit representations of cancer pathways from drug tumor sensitivity data of a cell line and utilize them to predict the sensitivities of a new drug given the kinase inhibitors of the drug and to design and measure the effectiveness of drug combination therapies.",
author = "Noah Berlow and Ranadip Pal",
year = "2011",
doi = "10.1109/gensips.2011.6169435",
language = "English",
isbn = "9781467304900",
series = "Proceedings - IEEE International Workshop on Genomic Signal Processing and Statistics",
publisher = "IEEE Computer Society",
pages = "36--37",
booktitle = "Proceedings 2011 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'11",
note = "null ; Conference date: 04-12-2011 Through 06-12-2011",
}