Abstract
A novel multi-component reaction for the synthesis of polyfunctionalized indoles and bis-indoles has been established. The reaction pathways were controlled by varying enamines with different substitution patterns to give polyfunctionalized indoles and bis-indoles selectively. The reaction proceeds at a fast speed within 15–30 min with water as the major byproduct, which makes work-up convenient.
Original language | English |
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Pages (from-to) | 808-810 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 48 |
Issue number | 6 |
DOIs | |
State | Published - Dec 14 2012 |