A macrocycle directed total synthesis of di-O-methylendiandrin A

Timothy H. Barnes, Kara F. Johnson, John Gorden, Bradley L. Merner

Research output: Contribution to journalArticlepeer-review

Abstract

The synthesis of di-<italic>O</italic>-methylendiandrin A has been achieved using diastereoselective, vicinal alkylation and transannular McMurry reactions of a macrocyclic 1,4-diketone, to establish stereochemistry and the strained ring of the natural product.
Original languageEnglish
Pages (from-to)8747-8749
JournalChemical Communications
DOIs
StatePublished - Nov 2020

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