A history of low birth weight alters recovery following a future head injury: A case series

Adam T. Schmidt, Xiaoqi Li, Kathy Zhang-Rutledge, Gerri R. Hanten, Harvey S. Levin

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objective: Low birth weight (LBW; below 2500 grams) is a general risk factor for a variety of neurodevelopmental difficulties. However, these children may remain more vulnerable to neurologic and environmental insults occurring years later. This prospective case series reports on children who sustained a mild, moderate, or severe traumatic brain injury (TBI) in middle childhood but who had also been born with birth weights below 2500 grams.Participants: Participants were 14 children with mild, moderate, or severe traumatic brain injury (TBI), 5 of whom had birth weights under 2500 grams (LBW) and 9 children with normal birth weight (NBW). All participants were drawn from a larger study on the long-term cognitive and behavioral impact of pediatric TBI and were matched on age, estimated socioeconomic status (SES), and severity of TBI (with NBW children actually having a slightly worse overall injury severity).Results: At baseline, both groups exhibited similar scores on WJ-R Letter Word Identification and Calculations, Tower of London number solved, and CVLT-C total correct. Baseline group differences were observed on the CELF-III Formulated Sentences (NBW > LBW) and on the VABS Adaptive Behavior Composite and Socialization subdomain (LBW > NBW). Over 2 years, relative to the NBW group, the LBW group evidenced declines on both WJ-R subtests, CVLT-C total correct, CELF-III Formulated Sentences, and VABS Adaptive Behavior Composite and Socialization.Conclusions: Although preliminary in nature due to small sample size, findings suggest a history of LBW influences the recovery trajectory following childhood TBI. Academic and adaptive functioning and verbal memory appeared particularly affected.

Original languageEnglish
Pages (from-to)495-508
Number of pages14
JournalChild Neuropsychology
Volume20
Issue number5
DOIs
StatePublished - Sep 3 2014

Keywords

  • Academic functioning
  • Adaptive functioning
  • Children
  • Development
  • Language
  • Low birth weight
  • Reading skills
  • Social adaptation
  • Traumatic brain injury
  • Verbal memory

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