A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors

Vighnesh Rudra Das; Donald Y.C. Lie; Tam Nguyen

doi:10.1109/MWSCAS.2014.6908470

A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors

Vighnesh Rudra Das, Donald Y.C. Lie, Tam Nguyen

Electrical and Computer Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

Abstract

This paper presents the design of a monolithic low power CMOS low-noise instrumentation amplifier (INA) for low-power biosensor applications. To achieve high-fidelity cardiac signal acquisition, the INA circuit and system design requirements are discussed. Design strategies for mitigating the in-band flicker noise and thermal noise using chopper-stabilization and current scaling techniques are investigated. Sub-threshold operation is also utilized to reduce power. The INA achieves a simulated noise spectral density of 39.9 nV/√Hz from dc to 300Hz in 4.6μW, with an outstanding noise efficiency factor (NEF) of 2.47.

Original language	English
Title of host publication	2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	535-538
Number of pages	4
ISBN (Electronic)	9781479941346, 9781479941346
DOIs	https://doi.org/10.1109/MWSCAS.2014.6908470
State	Published - Sep 23 2014
Event	2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014 - College Station, United States Duration: Aug 3 2014 → Aug 6 2014

Publication series

Name	Midwest Symposium on Circuits and Systems
ISSN (Print)	1548-3746

Conference

Conference	2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014
Country/Territory	United States
City	College Station
Period	08/3/14 → 08/6/14

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10.1109/MWSCAS.2014.6908470

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Das, V. R., Lie, D. Y. C., & Nguyen, T. (2014). A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors. In 2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014 (pp. 535-538). [6908470] (Midwest Symposium on Circuits and Systems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MWSCAS.2014.6908470

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title = "A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors",

abstract = "This paper presents the design of a monolithic low power CMOS low-noise instrumentation amplifier (INA) for low-power biosensor applications. To achieve high-fidelity cardiac signal acquisition, the INA circuit and system design requirements are discussed. Design strategies for mitigating the in-band flicker noise and thermal noise using chopper-stabilization and current scaling techniques are investigated. Sub-threshold operation is also utilized to reduce power. The INA achieves a simulated noise spectral density of 39.9 nV/√Hz from dc to 300Hz in 4.6μW, with an outstanding noise efficiency factor (NEF) of 2.47.",

author = "Das, {Vighnesh Rudra} and Lie, {Donald Y.C.} and Tam Nguyen",

note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; null ; Conference date: 03-08-2014 Through 06-08-2014",

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doi = "10.1109/MWSCAS.2014.6908470",

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Das, VR, Lie, DYC & Nguyen, T 2014, A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors. in 2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014., 6908470, Midwest Symposium on Circuits and Systems, Institute of Electrical and Electronics Engineers Inc., pp. 535-538, 2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014, College Station, United States, 08/3/14. https://doi.org/10.1109/MWSCAS.2014.6908470

A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors. / Das, Vighnesh Rudra; Lie, Donald Y.C.; Nguyen, Tam.

2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 535-538 6908470 (Midwest Symposium on Circuits and Systems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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N2 - This paper presents the design of a monolithic low power CMOS low-noise instrumentation amplifier (INA) for low-power biosensor applications. To achieve high-fidelity cardiac signal acquisition, the INA circuit and system design requirements are discussed. Design strategies for mitigating the in-band flicker noise and thermal noise using chopper-stabilization and current scaling techniques are investigated. Sub-threshold operation is also utilized to reduce power. The INA achieves a simulated noise spectral density of 39.9 nV/√Hz from dc to 300Hz in 4.6μW, with an outstanding noise efficiency factor (NEF) of 2.47.

AB - This paper presents the design of a monolithic low power CMOS low-noise instrumentation amplifier (INA) for low-power biosensor applications. To achieve high-fidelity cardiac signal acquisition, the INA circuit and system design requirements are discussed. Design strategies for mitigating the in-band flicker noise and thermal noise using chopper-stabilization and current scaling techniques are investigated. Sub-threshold operation is also utilized to reduce power. The INA achieves a simulated noise spectral density of 39.9 nV/√Hz from dc to 300Hz in 4.6μW, with an outstanding noise efficiency factor (NEF) of 2.47.

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BT - 2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014

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Das VR, Lie DYC, Nguyen T. A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors. In 2014 IEEE 57th International Midwest Symposium on Circuits and Systems, MWSCAS 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 535-538. 6908470. (Midwest Symposium on Circuits and Systems). https://doi.org/10.1109/MWSCAS.2014.6908470

A fully integrated low noise CMOS instrumentation amplifier design for low-power biosensors

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