• 3103 Citations (Scopus)
  • 29 h-Index
1972 …2019

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Scholarly Research

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Article
2018

Cytotoxicity of selenium immunoconjugates against triple negative breast cancer cells

Khandelwal, S., Boylan, M., Spallholz, J. E. & Gollahon, L., Nov 2018, In : International journal of molecular sciences. 19, 11, 3352.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cytotoxicity of Selenium Immunoconjugates Against Triple Negative Breast Cancer Cells

Khandelwal, S., Boylan, M., Spallholz, J. & Gollahon, L., Oct 26 2018, In : International Journal of Molecular Sciences. p. 1-29

Research output: Contribution to journalArticle

2017

Selenium-mediated arsenic excretion in mammals: A synchrotron-based study of whole-body distribution and tissue-specific chemistry

Ponomarenko, O., La Porte, P. F., Singh, S. P., Langan, G., Fleming, D. E. B., Spallholz, J. E., Alauddin, M., Ahsan, H., Ahmed, S., Gailer, J., George, G. N. & Pickering, I. J., Nov 2017, In : Metallomics. 9, 11, p. 1585-1595 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

25 hydroxy vitamin D is higher when a renal multivitamin is given with cholecalciferol at hemodialysis

Subih, H. S., Behrens, J., Burt, B., Clement, L., Pannell, R., Macha, L., Spallholz, J. & Boylan, M., 2016, In : Asia Pacific journal of clinical nutrition. 25, 4, p. 754-759 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

Plano, D., Karelia, D. N., Pandey, M. K., Spallholz, J. E., Amin, S. & Sharma, A. K., Mar 10 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 1946-1959 14 p.

Research output: Contribution to journalArticle

57 Scopus citations

Design , Synthesis and Biological Evaluation of Novel Selenium Molecules as Anti-Cancer Agents

Plano, D., Karelia, D. N., Pandley, M. K., Spallholz, J., Amin, S. & Sharma, A. K., Mar 10 2016, In : Default journal. p. 1946-1949

Research output: Contribution to journalArticle

Mean Serum 25 Hydroxy Vitamin D Levels are Higher in Hemodialysis Subjects Given a Renal Multivitamin with Cholecalciferol at Dialysis

Subih, H., Behrens, J., Burt, B., Clement, L., Pannell, R., Spallholz, J. & Boylan, M., Jan 2016, In : Default journal. p. epub

Research output: Contribution to journalArticle

Observation of the seleno bis-(S-glutathionyl) arsinium anion in rat bile

George, G., Gailer, J., Ponomarenko, O., LaPorte, P., Strait, K., Alauddin, M., Ahsan, H., Ahmed, S., Spallholz, J. & Pickering, I., Dec 2016, In : Default journal. p. 754-759

Research output: Contribution to journalArticle

Observation of the seleno bis-(S-glutathionyl) arsinium anion in rat bile

George, G. N., Gailer, J., Ponomarenko, O., La Porte, P. F., Strait, K., Alauddin, M., Ahsan, H., Ahmed, S., Spallholz, J. & Pickering, I. J., May 1 2016, In : Journal of Inorganic Biochemistry. 158, p. 24-29 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

Low Starch/Low Dairy Diet Results in Successful Treatment of Obesity and Co-Morbidities Linked to Polycystic Ovary Syndrome (PCOS). Journal of Obesity and Weight Loss Therapy

Phy, J., Pohlmeier, A., Cooper, J., Watkins, P., Spallholz, J., Harris, K., Berenson, A. & Boylan, M., Oct 2015, In : Default journal. p. 259

Research output: Contribution to journalArticle

Redox-active selenium compounds - from toxicity and cell death to cancer treatment

Misra, S., Boylan, M., Selvam, A., Spallholz, J. & Bjornstedt, M., May 13 2015, In : Default journal. p. 3536-3556

Research output: Contribution to journalArticle

Soft tissue measurement of arsenic and selenium in an animal model using portable X-ray fluorescence

Fleming, D. E. B., Groves, J. W., Gherase, M. R., George, G. N., Pickering, I. J., Ponomarenko, O., Langan, G., Spallholz, J. E., Alauddin, M., Ahsan, H., Ahmed, S. & La Porte, P. F., Nov 1 2015, In : Radiation Physics and Chemistry. 116, p. 241-247 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Effect of a low-starch/low-dairy diet on fat oxidation in overweight and obese women with polycystic ovary syndrome

Pohlmeier, A. M., Phy, J. L., Watkins, P., Boylan, M., Spallholz, J., Harris, K. S. & Cooper, J. A., Nov 16 2014, In : Applied Physiology, Nutrition and Metabolism. 39, 11, p. 1237-1244 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Effect of a low-starch/low-dairy diet on fat oxidation in overweight and obese women with polycystic ovary syndrome.

Pohlmeier, A., Phy, J., Watkins, P., Boylan, M., Spallholz, J., Harris, K. & Cooper, J., Aug 2014, In : Default journal. p. 1237-1244

Research output: Contribution to journalArticle

2012

Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: Thiol reactivity and its implications

Crampsie, M. A., Pandey, M. K., Desai, D., Spallholz, J., Amin, S. & Sharma, A. K., Oct 25 2012, In : Chemico-Biological Interactions. 200, 1, p. 28-37 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2011

Glucose and insulin levels are increased in obese and overweight mothers’ breast-milk.

Ahuja, S., Boylan, M., Roman-Shriver, C., Spallholz, J., Pence, B. & Sawyer, B., 2011, In : Default journal. p. 201-201

Research output: Contribution to journalArticle

Low-level groundwater arsenic exposure impacts cognition: A project FRONTIER study

Gong, G., Hargrave, K. A., Hobson, V., Spallholz, J., Boylan, M., Lefforge, D. & O'Bryant, S. E., Sep 2011, In : Journal of Environmental Health. 74, 2, p. 16-22 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Low-Level groundwater arsenic exposure impacts cognition: A project FRONTIER study.

Gong, G., Hobson, V., Hargrave, K. A., Spallholz, J., Boylan, M., Lafforge, D. & O'Bryant, S., 2011, In : Default journal. p. 661-874

Research output: Contribution to journalArticle

2010

) Phenylalkyl Isoselenocyanates vs. Isothiocyanates : Thiol Activity and its Implications.

Cramsie, M. A., Pandy, M. K., Spallholz, J., Desai, D., Spallholz, J. & Sharma, A. K., 2010, In : Chemico-Biological Interactions. p. 28-37

Research output: Contribution to journalArticle

Anti-oxdant-Prooxidant Properties of a New Organoselenium Library

Spallholz, J., 2010, In : Default journal. p. 7292-7312

Research output: Contribution to journalArticle

Antioxidant-prooxidant properties of a new organoselenium compound library

Plano, D., Baquedano, Y., Ibánez, E., Jiménez, I., Palop, J. A., Spallholz, J. E. & Sanmartín, C., Oct 2010, In : Molecules. 15, 10, p. 7292-7312 21 p.

Research output: Contribution to journalArticle

Open Access
62 Scopus citations

Anti-oxidant-Prooxidant Properties of a New Organoselenium Library

Plano, D., Baquesano, Y., Ibanez, E., Jimenez, I., Palop, J. A., Spallholz, J. & Sanmartin, C., 2010, In : Default journal. p. 7292-7312

Research output: Contribution to journalArticle

2009

Organoselenium coating on cellulose inhibits the formation of biofilms by Pseudomonas aeruginosa and Staphylococcus aureus

Tran, P. L., Hammond, A. A., Mosley, T., Cortez, J., Gray, T., Colmer-Hamood, J. A., Shashtri, M., Spallholz, J. E., Hamood, A. N. & Reid, T. W., Jun 2009, In : Applied and environmental microbiology. 75, 11, p. 3586-3592 7 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations
2008

Selenium and arsenic content of agricultural soils from Bangladesh and Nepal

Spallholz, J. E., Boylan, L. M., Robertson, J. D., Smith, L., Rahman, M. M., Hook, J. & Rigdon, R., Mar 2008, In : Toxicological and Environmental Chemistry. 90, 2, p. 203-210 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Selenium content of rice, mixed plant foods and fish from Bangladesh

Spallholz, J. E., Boylan, L. M., Rahman, M. M., Katz, D., Robertson, J. D., Zakaria, A. B. M., Khan, A. H., Alauddin, M., Bhattacharjee, M., Sultana, S., Khanam, S. & Choucair, Z., Mar 2008, In : Toxicological and Environmental Chemistry. 90, 2, p. 211-220 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Selenium-enriched garlic and cabbage as a dietary selenium source for broilers

Seo, T. C., Spallholz, J. E., Yun, H. K. & Kim, S. W., Dec 1 2008, In : Journal of Medicinal Food. 11, 4, p. 687-692 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Toxicity and mutagenicity of selenium compounds in Saccharomyces cerevisiae

Letavayová, L., Vlasáková, D., Spallholz, J. E., Brozmanová, J. & Chovanec, M., Feb 1 2008, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 638, 1-2, p. 1-10 10 p.

Research output: Contribution to journalArticle

88 Scopus citations
2007

Efficacy of dietary selenium sources on growth and carcass characteristics of growing-finishing pigs fed diets containing high endogenous selenium

Mateo, R. D., Spallholz, J. E., Elder, R., Yoon, I. & Kim, S. W., May 2007, In : Journal of animal science. 85, 5, p. 1177-1183 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Oxidation of glutathione and superoxide generation by inorganic and organic selenium compounds

Chen, J. J., Boylan, L. M., Wu, C. K. & Spallholz, J. E., 2007, In : BioFactors. 31, 1, p. 55-66 12 p.

Research output: Contribution to journalArticle

41 Scopus citations
2006

Prevention of bacterial colonization of contact lenses with covalently attached selenium and effects on the rabbit cornea

Mathews, S. M., Spallholz, J. E., Grimson, M. J., Dubielzig, R. R., Gray, T. & Reid, T. W., Aug 2006, In : Cornea. 25, 7, p. 806-814 9 p.

Research output: Contribution to journalArticle

58 Scopus citations
2005

Arsenic and selenium in human hair: A comparison of five countries with and without arsenicosis

Spallholz, J. E., Boylan, L. M., Palace, V., Chen, J., Smith, L., Rahman, M. M. & Robertson, J. D., Aug 2005, In : Biological Trace Element Research. 106, 2, p. 133-144 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Identification of water-soluble gamma-glutamyl-Se-methylselenocysteine in yeast-based selenium supplements by reversed-phase HPLC with ICP-MS and electrospray tandem MS detection

Infante, H. G., O'Connor, G., Rayman, M., Wahlen, R., Spallholz, J. E., Hearn, R. & Catterick, T., Sep 2005, In : Journal of analytical atomic spectrometry. 20, 9, p. 864-870 7 p.

Research output: Contribution to journalArticle

39 Scopus citations
2004
104 Scopus citations

Metabolism of selenomethionine by rainbow trout (Oncorhynchus mykiss) embryos can generate oxidative stress

Palace, V. P., Spallholz, J. E., Holm, J., Wautier, K., Evans, R. E. & Baron, C. L., May 2004, In : Ecotoxicology and Environmental Safety. 58, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

79 Scopus citations
126 Scopus citations
2002

Effect of Selenium Supplementation on Cytotoxic Activity of the Human NK Cell Line

Davis, R. L., Spallholz, J. E. & Phillips, C. A., Mar 6 2002, In : Journal of Nutritional Immunology. 5, 3-4, p. 99-113 15 p.

Research output: Contribution to journalArticle

Selenium biotransformations into proteinaceous forms by foodweb organisms of selenium-laden drainage waters in California

Spallholz, J. E. & Hoffman, D. J., 2002, In : Aquatic Toxicology. 57, 1-2, p. 65-84 20 p.

Research output: Contribution to journalArticle

142 Scopus citations
2000

Effect of dietary copper on selenium toxicity in Fischer 344 rats

Tatum, L., Shankar, P., Mallory Boylan, L. & Spallholz, J. E., 2000, In : Biological Trace Element Research. 77, 3, p. 241-249 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

The effects of dietary selenomethionine on polyamines and azoxymethane-induced aberrant crypts

Baines, A. T., Holubec, H., Basye, J. L., Thorne, P., Bhattacharyya, A. K., Spallholz, J., Shriver, B., Cui, H., Roe, D., Clark, L. C., Earnest, D. L. & Nelson, M. A., Nov 28 2000, In : Cancer Letters. 160, 2, p. 193-198 6 p.

Research output: Contribution to journalArticle

23 Scopus citations
1999

Selenium compounds have disparate abilities to impose oxidative stress and induce apoptosis

Stewart, M. S., Spallholz, J. E., Neldner, K. H. & Pence, B. C., Jan 1999, In : Free Radical Biology and Medicine. 26, 1-2, p. 42-48 7 p.

Research output: Contribution to journalArticle

1998

Dimethyldiselenide generates superoxide in an in vitro chemiluminescence assay in the presence of glutathione

Spallholz, J. E., Shriver, B. J. & Reid, T. W., Mar 20 1998, In : FASEB Journal. 12, 5, p. A825

Research output: Contribution to journalArticle

Inhibition of selenite-induced cytotoxicity and apoptosis in human colonic carcinoma (HT-29) cells by copper

Davis, R. L., Spallholz, J. E. & Pence, B. C., 1998, In : Nutrition and Cancer. 32, 3, p. 181-189 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
1997
31 Scopus citations

Copper inhibits selenite-induced cytotoxicity in human colonic carcinoma cells (HT29)

Davis, R. L., Spallholz, J. E. & Pence, B. C., 1997, In : FASEB Journal. 11, 3, p. A403

Research output: Contribution to journalArticle

Cytotoxicity of an internalizing 7E11-C5 Mab-Se immunoconjugate against DU145 prostate tumor cells

Chen, J., Boylan, M., Reid, T. W. & Spallholz, J. E., 1997, In : FASEB Journal. 11, 3, p. A403

Research output: Contribution to journalArticle

Cytotoxicity of selenium compounds to cultured normal primary human keratinocytes and squamous cell carcinoma cells

Stewart, M., Neldner, K., Spallholz, J. & Pence, B., 1997, In : FASEB Journal. 11, 3, p. A403

Research output: Contribution to journalArticle

Free Radical Generation by Selenium Compounds and Their Prooxidant Toxicity

Spallholz, J. E., Sep 1997, In : Biomedical and Environmental Sciences. 10, 2-3, p. 260-270 11 p.

Research output: Contribution to journalArticle

163 Scopus citations

In vitro and in vivo cytotoxicity of a B72.3 Mab-Se immunoconjugate against LS174T colon tumor cells

Spallholz, J. E., Boylan, M., Reid, T. W. & Chen, J., 1997, In : FASEB Journal. 11, 3, p. A518

Research output: Contribution to journalArticle